Recombinant Human Tollip Protein

Target Information

Sequence	MATTVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQQLQYGGAVG TVGRLNITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRW NKVIHCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLRQGKVEDK WYSLSGRQGDDKEGMINLVMSYALLPAAMVMPPQPVVLMPTVYQQGVGYV PITGMPAVCSPGMVPVALPPAAVNAQPRCSEEDLKAIQDMFPNMDQEVIR SVLEAQRGNK DAAINSLLQMGEEPVEHHHHHH
Sequence Similarities	Belongs to the tollip family. Contains 1 C2 domain. Contains 1 CUE domain.
Amino Acids	2 to 274
Cellular Localization	Cytoplasm.
Function	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.

Product Details

Product Type	Protein
Species	Human
Source	E. coli
Tag	His
Endotoxin Level	≥1.0 Eu/µg
Protein Length	Full length protein
Molecular Weight	31 kDa
Purity	>95%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.