Recombinant Mouse IL-34 Protein

Target Information

Sequence	MGSSHHHHHHSSGLVPRGSHMNENLEIWTLTQDKECDLTGYLRGKLQYKN RLQYMKHYFPINYRIAVPYEGVLRVANITRLQKAHVSERELRYLWVLVSL NATESVMDVLLEGHPSWKYLQEVQTLLENVQRSLMDVEIGPHVEAVLSLL STPGLSLKLVRPKALLDNCFRVMELLYCSCCKQSPILKWQDCELPRLHPH SPGSLMQCTATNVYPLSRQTPTSLPGSPSSSHGSLP
Sequence Similarities	Belongs to the IL-34 family.
Amino Acids	21 to 235
Cellular Localization	Secreted.
Tissue Specificity	Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Function	Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.

Product Details

Product Type	Protein
Species	Mouse
Source	E. coli
Tag	His
Protein Length	Full length protein
Molecular Weight	27 kDa
Purity	>85%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C.
Handling	Avoid freeze / thaw cycle.