Recombinant Mouse IL-6 Protein

Target Information

Sequence	Recombinant Murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues: MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITH VLWEIV EMRKELCNGN SDCMNNDDALAENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQRDTETLI HIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LK SLEEFLKVTLRSTRQT
Sequence Similarities	Belongs to the IL-6 superfamily.
Cellular Localization	Secreted.
Function	Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Product Details

Product Type	Protein
Species	Mouse
Source	E. coli
Protein Length	Full length protein
Purity	>98%
Active	Yes
Animal free	No
Nature	Recombinant
Application	FuncS, SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C.
Handling	Avoid freeze / thaw cycle.