Recombinant Mouse IRAKM Protein

Target Information

Sequence	MAGRCGARGALSPQLLLFDLPPALLGELCGILDSCDGPLGWRGLAERLSN SWLDVRHIEKYVNQGKSGTRELLWSWAQKNKTIGDLLEVLQDMGHQRAIH LIINYGVSWTPSVQTHHELPFPSFPPEVKHACRENDPGPLEPANVTVDNV LVPEHNEKGTLQKTPISFQSILEGTKHFHKDFLIGEGEIFEVYRVDIRNQ AYAVKLFKQEKKMQLKKHWKRFLSELEVLLLFRHPHILELAAYFTETEKL CLVYPYMSNGTLFDRLQCTNGTTPLSWHVRISVLIGIAKAIQYLHNTQPC AVICGNVSSANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKH LWYMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLL MELMEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMD EVLSSLESTQPSLYFAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDENQNN HSVPPKEVLGTDRVTQKTPFECSQSEVTFLGLDRNRGNRGSEADCNVPSS SHEECWSPELVAPSQDLSPTVISLGSSWEVPGHSYGSKPMEKRCSSGLFC SEHEQSKKQ
Sequence Similarities	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. Contains 1 death domain. Contains 1 protein kinase domain.
Amino Acids	1 to 609
Tissue Specificity	Expressed predominantly in peripheral blood lymphocytes.
Function	Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Product Details

Product Type	Protein
Species	Mouse
Source	Baculovirus Infected Insect Cells
Protein Length	Full length protein
Molecular Weight	68 kDa
Purity	>85%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.