RET-IN-11

Cat. No.: IBDI-436353

RET-IN-11 is a potent and selective RET inhibitor with IC50s of 6.20 nM, 18.68 nM for RET and RET V804M, respectively. RET-IN-11 shows anti-proliferation and migration activity in CCDC6-RET-driven LC-2/ad cells. RET-IN-11 induces cell apoptosis.

Product Details

Target	Apoptosis | RET
Molecular Weight	515.59
SMILES	O=C(NC1=CC=CC(F)=C1)CC2=CC=C(NC3=NC(N4CCN(C)CC4)=CC(NC5=CC(C)=NN5)=N3)C=C2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.