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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Ridaforolimus

Cat. No.: IBDI-434848

Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells.

Size (Solid):

Product Details

Target mTOR | Autophagy | Bacterial
Molecular Weight 990.21
Appearance Solid
Synonyms MK-8669, Deforolimus, AP23573
SMILES O=C([[email protected]@]1(O)[[email protected]@H](CC[[email protected]@H](C[[email protected]@H](/C(C)=C/C=C/C=C/[[email protected]](C[[email protected]@H](C)C([[email protected]@H]([[email protected]@H](/C(C)=C/[[email protected]]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[[email protected]]3C(O[[email protected]@H](CC2=O)[[email protected]@H](C[[email protected]@H]4C[[email protected]]([[email protected]](OP(C)(C)=O)CC4)OC)C)=O)=O
Purity 98.81%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
*The compound is unstable in solutions, freshly prepared is recommended.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.