RMS5

Cat. No.: IBDI-433761

RMS5, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property.

Product Details

Target	P-glycoprotein | Apoptosis
Molecular Weight	598.75
SMILES	COC1=C(OC(C=C([[email protected]@]2([H])CC3=CC=C(C=C3)O4)C(CCN2C)=C5)=C5OC)C([[email protected]]6([H])CC7=CC4=CS7)=C(CCN6C)C=C1OC

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.