RN-1734
Cat. No.: IBDI-437670
RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
TRP Channel |
| Molecular Weight |
353.31 |
| Appearance |
Solid |
| SMILES |
O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O |
| Purity |
99.86% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
