RNA polymerase II-IN-1

Cat. No.: IBDI-434864

RNA polymerase II-IN-1 (compound 19iv) is a amatoxin, inhibiting RNA polymerase II (Pol II) with an IC50 value of 36.66 nM. RNA polymerase II-IN-1 has higher cytotoxicity against cancer cells and less toxic in normal cells than α-Amanitin.

Product Details

Target	DNA/RNA Synthesis
Molecular Weight	887.96
SMILES	O=C([[email protected]@H](NC(CNC1=O)=O)[[email protected]](CC)C)NNC(N[[email protected]@H]2C(N[[email protected]](C(N3C[[email protected]@H](C[[email protected]]3C(N[[email protected]](C(N[[email protected]@H]1CC4=C(SC2)NC5=C4C=CC=C5)=O)[[email protected]]([[email protected]](CO)O)C)=O)O)=O)CC(N)=O)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.