RNA polymerase II-IN-2

Cat. No.: IBDI-434892

RNA polymerase II-IN-2 (compound 20iii) is a potent RNA polymerase II (Pol II) inhibitor with Ki value of 9.5 nM. RNA polymerase II-IN-2 has cytotoxicity against cancer cells, and exhibits 2 and 5 fold toxicity than α-amanitin against CHO and HEK293.

Product Details

Target	DNA/RNA Synthesis
Molecular Weight	915.02
SMILES	O=C([[email protected]](C(CC)CC)NC(CNC1=O)=O)NCC(N[[email protected]@H]2C(N[[email protected]](C(N3C[[email protected]@H](C[[email protected]]3C(N[[email protected]](C(N[[email protected]]1CC4=C(S[[email protected]]2C)NC5=C4C=CC=C5)=O)[[email protected]]([[email protected]](CO)O)C)=O)O)=O)CC(N)=O)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.