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Rodatristat

Cat. No.: IBDI-434955

Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.

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Product Details

Target 5-HT Receptor | Tryptophan Hydroxylase
Molecular Weight 561.98
Synonyms KAR5417
SMILES O=C([[email protected]]1NCC2(CCN(C3=NC(N)=NC(O[[email protected]](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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