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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Romidepsin

Cat. No.: IBDI-432227

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis.

Size (Solid):

Product Details

Target HDAC | Apoptosis
Molecular Weight 540.70
Appearance Solid
Synonyms FK 228, FR 901228, NSC 630176
SMILES C/C=C(NC([[email protected]@H](CSSCC/C=C/[[email protected]@H](O1)CC2=O)NC([[email protected]@H](C(C)C)N2)=O)=O)/C(N[[email protected]@H](C(C)C)C1=O)=O
Purity 99.85%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years
*The compound is unstable in solutions, freshly prepared is recommended.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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