RORγt agonist 2

Cat. No.: IBDI-432673

RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17).

Product Details

Target	ROR
Molecular Weight	585.64
SMILES	CC(C1N(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C(N[[email protected]](C4=CC=C(C=C4)S(CC)(=O)=O)CC#N)=O)C=C3OC1)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.