Rotigaptide

Cat. No.: IBDI-435904

Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation.

Product Details

Target	Gap Junction Protein
Molecular Weight	617.65
Appearance	Solid
Synonyms	ZP123
SMILES	O=C(N)CNC([[email protected]@H](C)NC(CNC([[email protected]@H]1N(C([[email protected]@H]2N(C([[email protected]@H](CC3=CC=C(O)C=C3)NC(C)=O)=O)CCC2)=O)C[[email protected]@H](O)C1)=O)=O)=O
Purity	99.88%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.