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RUSKI-201 dihydrochloride

Cat. No.: IBDI-433070

RUSKI-201 dihydrochloride is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 0.20 μM. RUSKI-201 dihydrochloride is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function.

Size (Solid):

Product Details

Target Hedgehog
Molecular Weight 430.43
SMILES CCC(CNCC(N1CCC2=C(C1C3=NC(C)=CC=C3)C=CS2)=O)C.Cl.Cl

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.