SAICAR-d1

Cat. No.: IBDI-436621

SAICAR-d is the deuterium labeled SAICAR. SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions.

Product Details

Target	Endogenous Metabolite
Molecular Weight	455.29
SMILES	O=C(O)C[[email protected]@H](C(O)=O)NC(C1=C(N)N([[email protected]]2[[email protected]@H]([[email protected]@H]([[email protected]@H]([[email protected]]([2H])OP(O)(O)=O)O2)O)O)C=N1)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.