SARS-CoV-2 Mpro-IN-5

Cat. No.: IBDI-434907

SARS-CoV-2 Mpro-IN-5 is a dual Inhibitor of Main Protease (M Pro) and Cathepsin L (CatL), with IC50s of 1800 nM and 145 nM respectively. SARS-CoV-2 Mpro-IN-5 has antiviral activity against SARS-CoV2. SARS-CoV-2 Mpro-IN-5 blocks SARS-CoV2 replication in hACE2 expressing A549 cells with IC50 value of 14.7 nM.

Product Details

Target	SARS-CoV
Molecular Weight	638.73
SMILES	O=C([[email protected]](NC(OC(C)(C)C)=O)CC1=CC=C(F)C=C1)N[[email protected]](C(N[[email protected]@H](C[[email protected]@H]2CCNC2=O)/C=C/C(OCC)=O)=O)CC3=CC=CC=C3

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.