sEH/AChE-IN-3

Cat. No.: IBDI-436310

sEH/AChE-IN-3 (compound (−)-15) is a potent and BBB-penetrated dual inhibitor of sEH (soluble epoxide hydrolase) and AChE (acetylcholinesterase), with IC50 values of 0.4 nM (hsEH), 1.94 nM (hAChE), 615 (hBChE, human butyrylcholinesterase), 4.3 nM (msEH), and 2.61 nM (mAChE), respectively.

Product Details

Target	Epoxide Hydrolase | CholinesteRase (ChE)
Molecular Weight	670.16
SMILES	O=C(NC1=CC=C(OC(F)(F)F)C=C1)NC2CCN(C(CCCCNC3=C([[email protected]]4([H])CC(C)=C[[email protected]](C4)([H])C5)C5=NC6=CC(Cl)=CC=C36)=O)CC2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.