Semaphorin 7a Monoclonal Antibody

Target Information

Target Name	Semaphorin 7a
Uniprot ID	O75326
Cellular Localization	Cell membrane. Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
Immunogen	Tissue, cells or virus corresponding to Human Semaphorin 7a.
Function	Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Product Details

Description	FITC Mouse monoclonal antibody to Semaphorin 7a.
Host Species	Mouse
Clonality	Monoclonal
Purity	Size exclusion
Isotype	IgM
Conjugation	FITC
Reactivity	Human
Immunogen	Tissue, cells or virus corresponding to Human Semaphorin 7a.
Application	Flo

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 8.0 Preservative: 0.097% Sodium Azide Constituent: PBS, 0.2% BSA