Shizukaol B

Cat. No.: IBDI-431186

Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression.

Product Details

Target	NO Synthase | COX | Interleukin Related | TNF Receptor
Molecular Weight	732.77
SMILES	COC(/C(C)=C1[[email protected]]2([H])[[email protected]@]34[[email protected]](CC5=C2[[email protected]]([[email protected]@]6([H])[[email protected]]5([H])C6)([[email protected]](C/1=O)O)C)([H])[[email protected]]7([[email protected]@]8([H])[[email protected]]([[email protected]@]9([[email protected]]7([H])CC3=C(COC(CCC(OC/C=C(C(OC9)=O)/C)=O)=O)C(O4)=O)O)([H])C8)C)=O
Structure Classification	Terpenoids>Sesquiterpenes

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.