SIGIRR Monoclonal Antibody - BSA and Azide Free

Target Information

Target Name	SIGIRR
Uniprot ID	Q6IA17
Cellular Localization	Membrane.
Immunogen	Synthetic peptide.
Function	Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Product Details

Description	Rabbit monoclonal antibody to SIGIRR - BSA and Azide Free.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Protein A purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Mouse, Rat, Human
Immunogen	Synthetic peptide.
Positive Control	IHC-P: Human kidney and colon tissue. Mouse kidney tissue. Rat kidney tissue WB: Hepa1-6 cell lysate. Mouse stomach, kidney, spleen and pancreas tissue lysate. Human stomach and fetal kidney lysate. Rat stomach and liver tissue lysate Flow Cyt (Intra): MEF and Hepa1-6 cells IP: Hepa1-6 whole cell lysate
Application	Flo, IHC-P, IP, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at 4 °C
Storage Buffer	pH: 7.2 Constituent: PBS
Handling	Do not freeze.