Cat. No.: IBDA-431766
Size:
Online InquiryTarget Information
Target Name | SIGIRR |
Uniprot ID | Q6IA17 |
Cellular Localization | Membrane. |
Immunogen | Synthetic peptide. |
Function | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
Product Details
Description | Rabbit monoclonal antibody to SIGIRR - BSA and Azide Free. |
Host Species | Rabbit |
Clonality | Monoclonal |
Purity | Affinity purified |
Isotype | IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Synthetic peptide. |
Application | WB |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at 4 °C |
Storage Buffer | pH: 7.2 Constituent: PBS |
Handling | Do not freeze. |