Cat. No.: IBDA-431577
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Online InquiryTarget Information
| Target Name | SIGLEC11 |
| Uniprot ID | Q96RL6 |
| Cellular Localization | Membrane. |
| Immunogen | Synthetic peptide. |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
Product Details
| Description | Rabbit monoclonal antibody to SIGLEC11. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Tissue culture supernatant |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Human fetal brain and fetal liver lysates. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |