Cat. No.: IBDA-431576
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Online InquiryTarget Information
| Target Name | SIGLEC11 |
| Uniprot ID | Q96RL6 |
| Cellular Localization | Membrane. |
| Immunogen | 18 amino acid peptide from near the carboxy terminus of Human SIGLEC11. |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
Product Details
| Description | Rabbit polyclonal antibody to SIGLEC11. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | 18 amino acid peptide from near the carboxy terminus of Human SIGLEC11. |
| Positive Control | HepG2 cell lysate Human liver tissue |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: PBS |