Cat. No.: IBDA-431529
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Online InquiryTarget Information
| Target Name | SIKE1 |
| Uniprot ID | Q9BRV8 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Recombinant fragment. |
| Function | Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways. |
Product Details
| Description | Rabbit monoclonal antibody to SIKE1. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Recombinant fragment. |
| Positive Control | SH-SY5Y, HeLa and HEK-293T cell lysates. Human kidney tissue. |
| Application | IHC-P, IP, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 40% Glycerol, 59% PBS, 0.05% BSA |
| Handling | Avoid freeze-thaw cycles. |