Cat. No.: IBDA-431527
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Online InquiryTarget Information
| Target Name | SIKE1 |
| Uniprot ID | Q9BRV8 |
| Cellular Localization | Cytoplasm. |
| Immunogen | Corresponding to C terminal amino acids 124-200 of Human SIKE1. |
| Function | Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways. |
Product Details
| Description | Rabbit polyclonal antibody to SIKE1. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Corresponding to C terminal amino acids 124-200 of Human SIKE1. |
| Positive Control | IHC-P: Human rectum tissue. WB: RH-30 human cell lysate. |
| Application | IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Upon delivery aliquot. Store at -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: 59% PBS, 40% Glycerol |
| Handling | Avoid freeze-thaw cycles. |