Simvastatin acid ammonium

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Cat. No.: IBDI-430465

Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	HMG-CoA Reductase (HMGCR) \| Reactive Oxygen Species
Molecular Weight	453.61
Appearance	Solid
Synonyms	Tenivastatin ammonium
SMILES	O=C(C[[email protected]@H](C[[email protected]@H](CC[[email protected]]1[[email protected]](C=CC2=C[[email protected]@H](C[[email protected]@H]([[email protected]]12[H])OC(C(C)(CC)C)=O)C)C)O)O)[O-].[NH4+]
Structure Classification	Ketones, Aldehydes, Acids
Purity	99.32%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.