Simvastatin acid calcium hydrate

Cat. No.: IBDI-433068

Simvastatin acid (Tenivastatin) calcium hydrate is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid calcium hydrate reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid calcium hydrate can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

Product Details

Target	HMG-CoA Reductase (HMGCR) | Reactive Oxygen Species
Synonyms	Tenivastatin calcium hydrate
SMILES	CCC(C)(C)C(O[[email protected]@H]1[[email protected]@]2([H])C(C=C[[email protected]@H]([[email protected]@H]2CC[[email protected]@H](O)C[[email protected]@H](O)CC(O)=O)C)=C[[email protected]@H](C1)C)=O.[1/2Ca].[xH2O]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.