Simvastatin hydroxy acid sodium

Cat. No.: IBDI-433069

Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

Product Details

Target	HMG-CoA Reductase (HMGCR) | Reactive Oxygen Species
Molecular Weight	458.56
Synonyms	Tenivastatin sodium, Simvastatin Impurity A sodium
SMILES	CCC(C)(C)C(O[[email protected]@H]1[[email protected]@]2([H])C(C=C[[email protected]](C)[[email protected]@H]2CC[[email protected]@H](O)C[[email protected]@H](O)CC(O[Na])=O)=C[[email protected]](C)C1)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.