SKAP55 Monoclonal Antibody

Target Information

Target Name	SKAP55
Uniprot ID	Q86WV1
Cellular Localization	Cytoplasm. Nucleus. Cell membrane. Upon T-cell stimulation, translocates to lipid rafts at the cell membrane.
Immunogen	Synthetic peptide within Human SKAP55 aa 50-150 (Cysteine residue).
Function	Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.

Product Details

Description	Rabbit monoclonal antibody to SKAP55.
Host Species	Rabbit
Clonality	Monoclonal
Purity	Tissue culture supernatant
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide within Human SKAP55 aa 50-150 (Cysteine residue).
Positive Control	Molt4 cells, Hut 78 cell line lysate, Human thymus tissue lysate,
Application	Flo, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.20 Preservative: 0.01% Sodium Azide Constituent: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue Culture Supernatant
Handling	Avoid freeze-thaw cycles.