Cat. No.: IBDA-431718
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Online InquiryTarget Information
| Target Name | SKAP55 |
| Uniprot ID | Q86WV1 |
| Cellular Localization | Cytoplasm. Nucleus. Cell membrane. Upon T-cell stimulation, translocates to lipid rafts at the cell membrane. |
| Immunogen | Synthetic peptide. |
| Function | Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. |
Product Details
| Description | Rabbit monoclonal antibody to SKAP55. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Tissue culture supernatant |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide. |
| Positive Control | Human thymus, Jurkat, HuT-78 and MOLT4 lysates, Jurkat cells |
| Application | Flo, ICC/IF, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.01% Sodium Azide Constituent: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |