Cat. No.: IBDA-431985
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Online InquiryTarget Information
| Target Name | SLAM/CD150 |
| Uniprot ID | Q13291 |
| Cellular Localization | Cell membrane. Present on the surface of B-cells and T-cells. |
| Immunogen | Synthetic peptide within Human SLAM/ CD150 aa 250-350. |
| Function | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
Product Details
| Description | Rabbit monoclonal antibody to SLAM / CD150. |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Synthetic peptide within Human SLAM/ CD150 aa 250-350. |
| Positive Control | WB: Jurkat, HuT 78, MOLT4, Daudi and human thymus lysates. Flow Cyt (Intra): Raji cells. |
| Application | Flo, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.2 Preservative: 0.05% Sodium Azide Constituent: 0.1% BSA, 40% Glycerol, 9.85% Tris Glycine, 50% Tissue Culture Supernatant |
| Handling | Avoid freeze-thaw cycles. |