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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

SMI-4a

Cat. No.: IBDI-436178

SMI-4a (TCS-PIM-1-4a) is a pan-Pim kinases inhibitor that blocks mTORC1 activity via activation of AMPK. SMI-4a kills a wide range of both myeloid and lymphoid cell lines (IC50 values ranging from 0.8 μM to 40 μM).

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Pim | Apoptosis
Molecular Weight 273.23
Appearance Solid
Synonyms TCS-PIM-1-4a
SMILES O=C(NC/1=O)SC1=C\C2=CC=CC(C(F)(F)F)=C2
Purity 99.63%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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