SNIPER(ER)-87

Cat. No.: IBDI-432350

SNIPER(ER)-87 consists of an inhibitor of apoptosis protein (IAP; ) ligand LCL161 derivative that is conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen by a PEG linker, and efficiently degrades the ERα protein (IC50=0.097 μM). SNIPER(ER)-87 preferentially recruits XIAP; to ERα in the cells, and XIAP; is the primary E3 ubiquitin ligase responsible for the SNIPER(ER)-87-induced ERα degradation.

Product Details

Target	SNIPERs | Estrogen Receptor/ERR
Molecular Weight	1044.30

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.