Solithromycin

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Cat. No.: IBDI-432334

Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC50s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Bacterial \| Antibiotic
Molecular Weight	845.01
Appearance	Solid
Synonyms	CEM-101, OP-1068
SMILES	C[[email protected]]([[email protected]](OC([[email protected]@](F)(C([[email protected]](C)[[email protected]]1O[[email protected]@](O[[email protected]](C)C[[email protected]@H]2N(C)C)([H])[[email protected]@H]2O)=O)C)=O)CC)(O3)[[email protected]]([[email protected]](C([[email protected]@H](C[[email protected]@]1(C)OC)C)=O)C)([H])N(CCCCN4C=C(C5=CC(N)=CC=C5)N=N4)C3=O
Purity	99.50%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.