Spliceostatin A

Cat. No.: IBDI-432388

Spliceostatin A, the FR901464 (HY-16212) methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia (CLL) cells.

Product Details

Target	Others
Molecular Weight	521.64
SMILES	C[[email protected]]1C[[email protected]@H](NC(/C=C\[[email protected]@H](OC(C)=O)C)=O)[[email protected]@H](C)O[[email protected]]1C/C=C(C)/C=C/[[email protected]@H]2[[email protected]@H](O)[[email protected]]3(CO3)C[[email protected]@](C)(OC)O2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.