SPR inhibitor 3
Cat. No.: IBDI-436479
SPR inhibitor 3 (SPRi3) is a potent sepIAP; terin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels.
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
Target |
Others |
Molecular Weight |
262.30 |
Appearance |
Solid |
Synonyms |
SPRi3 |
SMILES |
O=C(NCCC1=C(C)NC2=C1C=C(O)C=C2)COC |
Purity |
99.84% |
Storage & Handling
Shipping |
Room temperature in continental US. May vary elsewhere. |
Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.