Cat. No.: IBDA-430186
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Online InquiryTarget Information
| Target Name | STEAP1/STEAP |
| Synonyms | STEAP1 | Metalloreductase STEAP1 | PRSS24 | STEAP |
| Uniprot ID | Q9UHE8 |
| Immunogen | An 18 amino acid peptide located near the C-Terminus of human STEAP1. |
Product Details
| Description | STEAP antibody is an unconjugated rabbit polyclonal antibody to human STEAP (STEAP1) (C-Terminus). Tested on 20 paraffin-embedded human tissues. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Affinity purified |
| Conjugation | Unconjugated |
| Modifications | Unmodified |
| Reactivity | Human |
| Specificity | Recognizes STEAP1 (six transmembrane epithelial antigen of the prostate), a 39kD protein which is a member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. Does not cross-react with other STEAP-proteins. |
| Immunogen | An 18 amino acid peptide located near the C-Terminus of human STEAP1. |
| Application | IHC, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | PBS, 0.02% Sodium Azide |
| Handling | Avoid freeze-thaw cycles. |