Cat. No.: IBDA-431351
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Online InquiryTarget Information
| Target Name | TAB2 |
| Uniprot ID | Q9NYJ8 |
| Cellular Localization | Membrane. Cytoplasm > cytosol. Following IL1 stimulation, translocation occurs from the membrane to cytosol. |
| Immunogen | Recombinant full length protein within Human TAB2 aa 1 to the C-terminus. |
| Function | Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development. |
Product Details
| Description | Mouse polyclonal antibody to TAB2. |
| Host Species | Mouse |
| Clonality | Polyclonal |
| Purity | Protein A purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant full length protein within Human TAB2 aa 1 to the C-terminus. |
| Positive Control | TAB2 transfected 293T cell lysate. |
| Application | WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.4 Constituent: 100% PBS |
| Handling | Avoid freeze-thaw cycles. |