Cat. No.: IBDA-431349
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Online InquiryTarget Information
| Target Name | TAB2 |
| Uniprot ID | Q9NYJ8 |
| Cellular Localization | Membrane. Cytoplasm > cytosol. Following IL1 stimulation, translocation occurs from the membrane to cytosol. |
| Immunogen | Recombinant fragment corresponding to Human TAB2 aa 300-400. |
| Function | Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development. |
Product Details
| Description | Rabbit polyclonal antibody to TAB2. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | Recombinant fragment corresponding to Human TAB2 aa 300-400. |
| Positive Control | ICC/IF: MCF7 cells. |
| Application | ICC/IF |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Short term: 4 °C. Long term: -20 °C |
| Storage Buffer | pH: 7.20 Preservative: 0.02% Sodium Azide Constituent: 40% Glycerol, PBS |
| Handling | Avoid freeze-thaw cycles. |