Taccalonolide B

Cat. No.: IBDI-431013

Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.

Product Details

Target	Microtubule/Tubulin
Molecular Weight	660.71
SMILES	C[[email protected]]1([[email protected]]2([H])C[[email protected]](O3)[[email protected]]3[[email protected]@H]1OC(C)=O)[[email protected]]4([H])[[email protected]]([[email protected]@H](O)C2=O)([H])[[email protected]@]5([H])[[email protected]@](C)([[email protected]]6([H])[[email protected]@]([[email protected]](C(OC7=O)=C[[email protected]]6C)([[email protected]@]7(O)C)C)([H])[[email protected]@H]5O)[[email protected]@H](OC(C)=O)[[email protected]]4OC(C)=O
Structure Classification	Steroids

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.