Talmapimod hydrochloride

Cat. No.: IBDI-435833

Talmapimod (SCIO-469) hydrochloride is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod hydrochloride shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Product Details

Target	p38 MAPK
Molecular Weight	549.46
Synonyms	SCIO-469 hydrochloride
SMILES	O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[[email protected]](C)CN(CC4=CC=C(F)C=C4)[[email protected]@H](C)C3)=O)C(Cl)=C2)=O.[H]Cl

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.