Taltobulin trifluoroacetate

Cat. No.: IBDI-432554

Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.

Product Details

Target	Microtubule/Tubulin | ADC Cytotoxin | Apoptosis
Molecular Weight	587.67
Appearance	Solid
Synonyms	HTI-286 trifluoroacetate, SPA-110 trifluoroacetate
SMILES	CC(C)(C)[[email protected]](NC([[email protected]](C(C)(C1=CC=CC=C1)C)NC)=O)C(N([[email protected]@H](C(C)C)/C=C(C(O)=O)\C)C)=O.O=C(O)C(F)(F)F
Purity	99.96%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.