Tamnorzatinib
Cat. No.: IBDI-435533
Tamnorzatinib (ONO-7475) is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. Tamnorzatinib sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. Tamnorzatinib combines with Osimertinib (HY-15772) provides a bright promise for the study of?EGFR-mutated non-small cell lung cancer (NSCLC).
Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution
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Product Details
| Target |
TAM Receptor | Trk Receptor |
| Molecular Weight |
562.57 |
| Appearance |
Solid |
| Synonyms |
ONO-7475 |
| Purity |
98.07% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
