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TEI-9647

Cat. No.: IBDI-437482

TEI-9647, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease.

Size (Solid):

Product Details

Target VD/VDR
Molecular Weight 426.59
Appearance Solid
SMILES O=C1O[[email protected]@H](C[[email protected]]([[email protected]]2CC[[email protected]@]3([H])/C(CCC[[email protected]]23C)=C/C=C4C([[email protected]@H](O)C[[email protected]](O)C\4)=C)C)CC1=C
Purity 98.37%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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