Temozolomide-d3

Cat. No.: IBDI-436030

Temozolomide-d3 is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.

Product Details

Target	DNA Alkylator/Crosslinker | Autophagy | Apoptosis
Molecular Weight	197.17
Appearance	Solid
SMILES	O=C(N1C=N2)N(N=NC1=C2C(N)=O)C([2H])([2H])[2H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.