TFB-TBOA

Cat. No.: IBDI-435351

TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs.

Product Details

Target	EAAT2
Molecular Weight	426.34
Appearance	Solid
Synonyms	CF3-Bza-TBOA
SMILES	O=C(C1=CC=C(C=C1)C(F)(F)F)NC2=CC(CO[[email protected]](C(O)=O)[[email protected]](N)C(O)=O)=CC=C2
Purity	99.28%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.