TICAM2 Monoclonal Antibody

Target Information

Target Name	TICAM2
Uniprot ID	Q86XR7
Cellular Localization	Cytoplasm. Golgi apparatus. Cell membrane. Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane.
Immunogen	Synthetic peptide corresponding to Human TICAM2 aa 200 to the C-terminus conjugated to keyhole limpet haemocyanin.
Function	Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1.

Product Details

Description	Mouse monoclonal antibody to TICAM2.
Host Species	Mouse
Clonality	Monoclonal
Purity	IgG fraction
Isotype	IgG1
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide corresponding to Human TICAM2 aa 200 to the C-terminus conjugated to keyhole limpet haemocyanin.
Positive Control	Recombinant Human TICAM2 protein can be used as a positive control in WB. This antibody gave a positive signal in Human Kidney and Human Spleen Tissue Lyates
Application	Flo, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Upon delivery aliquot. Store at -20 °C or -80 °C
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide
Handling	Avoid freeze-thaw cycles.