TICAM2 Polyclonal Antibody

Target Information

Target Name	TICAM2
Uniprot ID	Q86XR7
Cellular Localization	Cytoplasm. Golgi apparatus. Cell membrane. Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane.
Immunogen	Synthetic peptide (Human) (C terminal).
Function	Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1.

Product Details

Description	Rabbit polyclonal antibody to TICAM2.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Ion Exchange Chromatography
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide (Human) (C terminal).
Positive Control	PC3 whole cell lysate.
Application	ICC/IF, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.2 Preservative: 0.02% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.