Cat. No.: IBDA-435157
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Online InquiryTarget Information
| Target Name | TLR2 |
| Uniprot ID | O60603 |
| Cellular Localization | Membrane. |
| Immunogen | Mouse TLR2 peptide. |
| Function | Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. |
Product Details
| Description | FITC Mouse monoclonal antibody to TLR2. |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Purity | Protein G purified |
| Isotype | IgG1 |
| Conjugation | FITC |
| Reactivity | Mouse, Human |
| Immunogen | Mouse TLR2 peptide. |
| Positive Control | Flow Cyt: RAW264.7 and THP-1 cells. |
| Application | Flo |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at 4 °C |
| Storage Buffer | Preservative: 0.02% Sodium Azide Constituent: PBS, 1% BSA |